ITTC Project


Unified Data Format for Mass Spectrometry Analysis (UDF)

Project Award Date: 01-13-2005



Description

Despite the similarity of information content across a wide variety of vendor-specific mass spectrometry formats (i.e., the pervasive mass/charge ratio), tools developed to process the data coming from one instrument are rarely capable of processing data derived from another platform. There is a great desire to be able to do so, since specific analysis options available on one platform are often of value to (and unavailable to) data arising from another. This communications issue can be largely overcome by: a) constructing a set of conversion routines to deposit all data (except that . arising from a small number of vendors that contractually forbid format reverse- . engineering) into a consistent and unified format, and by developing commensurate routines for back-converting from this unified format to vendor specific structures.

University of Kansas researchers are developing a suite of data conversion and compression routines capable of generating compact repositories of mass spectrometry data in a unified format suitable for efficient analysis and rapid reconstitution to vendor-specific form. Such a suite will permit the data from multiple mass spectrometric platforms to be amalgamated into a single, homogeneous form suitable for collective analysis. It will also allow data to be accessible to interrogation by a much broader slate of vendor supplied analysis tools than is currently the case. By storing the unified-format in a highly compressed form with efficient compression / extraction schemes, researchers hope to help establish a sensible standard for data intensive endeavors such as proteomics and lipidomics. Having established such a standard, researchers envision that niche analysis methods (e.g., isotope signature identification, contaminant elimination, recognition of post-translational modifications, etc.) that may not currently be available within slate of vendor-provided tools, can be programmed to operate in an efficient fashion on the standardized compressed data medium.


Investigators

Faculty Investigator(s): John Gauch

Student Investigator(s): Praveen Lakkaraju


Project Sponsors


Primary Sponsor(s): Kansas Idea Network of Biomedical Research Excellence (KINBRE)-NIH


Partner with ITTC

The Information and Telecommunication Technology Center at the University of Kansas has developed several assistance policies that enhance interactions between the Center and local, Kansas, or national companies. 

ITTC assistance includes initial free consulting (normally one to five hours). If additional support is needed, ITTC will offer one of the following approaches: 

Sponsored Research Agreement

Individuals and organizations can enter into agreements with KUCR/ITTC and provide funds for sponsored research to be performed at ITTC with the assistance of faculty, staff and students.

Licensing and Royalty/Equity Agreement

An ITTC goal is the development of investment-grade technologies for transfer to, and marketing by, local, Kansas, and national businesses. To enhance this process, the Center has developed flexible policies that allow for licensing, royalty, and equity arrangements to meet both the needs of ITTC and the company.

Commercialization Development

Companies with a technology need that can be satisfied with ITTC's resources can look to us for assistance. We can develop a relationship with interested partners that will provide for the development of a technology suited for commercialization.

ITTC Resource Access

ITTC resources, including computers and software systems, may be made available to Kansas companies in accordance with the Center's mission and applicable Regents and University policies.

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